how to wean off methimazole

By using this Site you agree to the following, By using this Site you agree to the following. You should go off it slowly. To become an empowered patient, you need to obtain a copy of any medical documentation done on you, either lab tests or reports from other physicians and keep your own file so you can see your progresss. A list of national and international resources and hotlines to help connect you to needed health and medical services. I'm not on meds yet but I agree with AnnLW. appropriate medical assistance immediately. Increased risk of infection. Am Fam Physician. Two weeks ago my tsh was 4.70 then on the 19 th of this month it was 5.02 ref range is 0.34-4.82. I said ok, not thinking anything of it, but after halving my dose for a few weeks Ive started to feel bad again. swollen, painful, or tender lymph glands in the neck, armpit, or groin. What Should You Expect When You Arrive at the Medical Office Late? Hi, The dose is taken in 3 divided doses every 8 hours. I hadn't tested much in over a year- hoping this prior post link will work on this post to refresh anyone's memory who cares to 27M, 6'0, 174lb, Been on NP for about 4 months, Don't smoke or drink. Saturday evening, I took my blood pressure, and the systolic reading was over 200. Could the anxiety be stemming from you actually still needing the methimazole? You pituitary is trying to tell your thyroid to produce more hormones, but the Methimazole (anti-thyroid med) is preventing your thyroid from working. why does this happen? I DONT KNOW IF I COULD STILL BE HYPER.MY LAB RESULTS HAAVE BEEN NORMAL FOR 1 YEAR. Being short tempered can go along with being fatigued and/or depressed or not feeling well in general. And other symptoms of hypothyroidism. Serious and sometimes fatal infections may occur during treatment with methimazole. Endocrinologic emergencies often fall at the wayside and are not generally considered as a possible diagnosis up front in patients in the emergency department who meet the criteria for systemic inflammatory response syndrome (SIRS). A relatively low dose of Methimazole was prescribed, along with Lisinopril, and Metoprolol. If you are hypothyroidwhether due to Hashimoto's, Graves' disease treatment, thyroid surgery, or congenital hypothyroidismfailing to take your thyroid hormone replacement medication can pose many risks to your health. Dosage form: oral tablet (10 mg; 5 mg) Thyrotoxic Crisis Oral Some clinicians recommend 60-80 mg daily. I hope you go into remission and you dont have to keep taking those god forsaken meds. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. I was taking a dosage of forty, then cut it down to twenty for about two weeks, and then was taken off of it entirely. So I now went to Winthrop Hospital and am off 5 mg of methimazole since I'm taking the nuclear test this week. You can think of the mainstay treatment strategies of thyroid storm based on three main goals (what I like to call the 3 Bs of thyroid storm soccer): The agents are discussed below along with some EM pharmacy pearls that may be beneficial to those of you practicing in the emergency department. If true allergy to iodine or contraindication to iodine therapy (e.g. Sorry you're having these problems. ACMT Toxicology Visual Pearl: Is the Silver Bullet for Refractory Vasoplegia Really Blue? unable to get any financial help*SSI/DISABILITY DENIED X4, ***this post is edited by moderator *** *** private e-mails not allowed*** Please read our Terms of Use. Initial dose: Mild hyperthyroidism: 15 mg orally per dayModerately severe hyperthyroidism: 30 to 40 mg orally per daySevere hyperthyroidism: 60 mg orally per day Maintenance dose:5 to 15 mg orally per day Comments: Daily doses are usually given in 3 divided doses at approximately 8 hour intervalsUses: -For the treatment of Graves' disease with hyperthyroidism or toxic multinodular goiter in whom surgery or radioactive iodine therapy is not an appropriate treatment option.-To ameliorate symptoms of hyperthyroidism in preparation for thyroidectomy or radioactive iodine therapy. Is There a Best Time to Take Your Thyroid Medication? over a year ago. Methimazole is used to treat hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. A list of national and international resources and hotlines to help connect you to needed health and medical services. Stop using methimazole and call your doctor right away if you have signs of infection such as: sudden weakness or ill feeling, fever, chills, sore throat, cold or flu symptoms; painful mouth sores, pain when swallowing, red or swollen gums; or. Unfortunately, there isn't a natural or herbal replacement for thyroid hormone. Home Treatment For Low Thyroid: What Essential Oils Are Good For Hypothyroidism? Having irrational thoughts worries. If a child is using this medicine, tell your doctor if the child has any changes in weight. manic bipolar unable to get along with others. You should not shock your body that way. Your hair loss or hair thinning may also be a symptom of hyperthyroidism, when your thyroid gland is overactive and makes too much thyroid hormone. i teally feel I have late stage chronic lime. Hello I'm glad I found this. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. I am a 52 year old female and I had been on 15MG Methimazole for the over 2 months and my Endo lower the dosage to 10MG (took the And I vote you find another endo even if you do even out - you want someone who knows their stuff to monitor you in case you relapse in the future. Thyroid storm. Propylthiouracil (PTU; 5 to 10 mg/kg per day) is also effective . I have nevery had anxiety attacks before. They took blood work and X-rays, and this went on for over 4 hours. I do have Hashitoxicosis so I remember you saying that I won't respond as well to methimazole. If you don't feel better after taking your medication for several months, you may need a dose adjustment or a different medicationnot a complete stop of your regimen. I was on 5 mg once a day. Mary Shomon is a writer and hormonal health and thyroid advocate. You will learn what these results mean very quickly and you can always learn more about them online. As far as symptoms go, I have been gassy (for no reason), fatigued more than usual, depressed, short tempered,and I'm either too cold or too hot. However, thyroid disease is complicated, and you can develop new symptoms when you begin your treatment, either due to the wrong medication dose or the way that your body responds to the medication. My T3 and T4 are at mid to lower end of the range. Methimazole may also be used for purposes not listed in this medication guide. Now down to 5 mg a day, 6 days a week (so 30 mg a week). Ive been on the 5 mg daily for a few years now. Herpes sores blister, then burst, scab and heal. I was taken to jail where I was geld for two weeks without my medicine and let me tell you I got sick with peripheral edema, vasculitis. Treatment of hyperthyroidism with a combination of methimazole and cholestyramine. I'd love to be able to start these again once I'm diagnosed and under the care of a naturopath. 2. All rights reserved. first cutting the 5mg tablet in half then in 1/4's. Same as sudden weather changes, we get headaches etc. I was diagnosed with Autoimmune Hyperthyroidism in Dec., 2006. She has a past medical history of hypertension and she has been compliant with her medications. Methimazole is an antithyroid medicine. I started off with relatively normal levels but my doc found nodules. One thing my Endo and I agree on is that he will not stop a patient's medication entirely unless their antibody levels are within the normal range even if all their thyroid labs are normal. Serious and sometimes fatal infections may occur during treatment with methimazole. Diagnosis of thyroid storm can be somewhat of a challenge because of this, but a scoring system developed by Burch and Wartofsky 1 can assist in determining the likelihood of thyroid storm in patients based on presenting signs and symptoms. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. This was very irresponsible of them and I was not able to be well enough to work for a year after that. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Swollen hands, feet, and face. Center for Hormonal Health and Well-Being, Low body temperature;constantly feeling cold, Weight gain; inability to lose weight despite diet and exercise, Infertility, miscarriage, stillbirth, or premature labor, Dramatically increased appetite and thirst. Vancomycin Loading Doses in Pediatric Patients: A Missed Opportunity? Now I have to start all over again. There may be two explanations for this benefit of long-term therapy, according . Helpful - 0 Comment leilajax Gimel is right, it only has a 6 hour half life. Call your doctor at once if you have: liver problems--nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Got dosage down to 5mgs. Not taking your hypothyroid or hyperthyroid medication can cause undesirable, dangerous, and even life-threatening conditions, ranging from fatigue and changes in blood pressure to death. I have been told by every doctor that I've seen in the past few months that it is a serious med, and even though I was only on it for mere months it could have done damage. Skip the missed dose if it is almost time for your next scheduled dose. You will be able to stop your methimazole or PTU immediately. Then I tried one 500 mg capsule and saw how I felt on it beofre I raised it to the dose that was mentioned in the research article. PMID: 24176474. Birth defects an option due to untreated Graves' disease? I have been taking the same dosages for all those years, except my dosage for Methimazole was brought down to 1 and 1/2 pills (5 mg pills) about a year ago. Yet many hypo sufferers complain of it as well. By learning about your labs and what they mean and following your body symptoms, you will have more information and be more prepared for discussions with your physician. Sulfamethoxazole-Trimethoprim for Skin and Soft Tissue Infections: 1 or 2 Tablets BID? She enjoys giving lectures and writing articles for both the lay public and medical audiences. I just have to say thanks for always replying to my posts. My doctor took me completely off Methimazole at 1 year with very poor resultsI was off the charts in 2 1/2 weeks and back up to 20MG a day to get me stable. I retired in 2015 because I was unable to work. Maybe paid for by government or yourself or medical plan, but still you are the one who has the right to say. This is perfect for me. Follow all directions on your prescription label. Again, be sure to discuss any concerns with your doctor and do not stop taking your medication without consulting with them first. Natural Solutions For Graves' Disease & Hashimoto's Thyroiditis. Create an account to follow your favorite communities and start taking part in conversations. You will be able to stop your cholestyramine (if on it) immediately. The state patrol who should be serving and protecting, was searching to destroy based on my appearance bulging eyes, unable to hold head back and count due to goiter,and the yellowing eyes and tremors crawling skin causes jerking movements. Methimazole is an excellent medication for Grave's disease and other forms of hyperthyroidism which works by interfering with the production of the thyroid hormones. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. over a year ago. It becomes too easy to label them as septic, and we may forget that endocrinologic emergencies, specifically thyroid storm, can present in very much the same way. ALiEM AIR Series | Orthopedics Lower Extremity Module. They told me to do that when I was taking 4 pills a day (20 mg) to get a test. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. This article covers the possible risks of not taking your hypothyroidism or hyperthyroidism medication. My gut feeling is that this method seems to make greater ense than the shock and confusion of going 'cold-turkey'. We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. All lab work has come back in normal ranges. Has anyone elses doctor done this? I'm not in hypo yet I don't think the doctors just think that I'm going into hypo..? It is also used before thyroid surgery or radioactive iodine treatment. Your blood may need to be tested often. It can also increase the risk of developing a dangerous condition known asthyroid storm, which has a high fatality rate. This exact thing happened to me and then my endo put me back on it and my body couldnt tolerate it I was passing out and my symptoms were so much worse,. That is a real challenge but I know one lady with both Graves and Hashi's who got treated by a Naturopath who was able to keep her thyroid levels normal with just the natural methods. nausea, vomiting, upset stomach; headache, dizziness, drowsiness; numbness or tingly feeling; rash, itching, skin discoloration; muscle or joint pain; hair loss; or. So I don't think there is one size fits all but I do believe you need the information from the tests your doc does as well as learning about your body and its symptoms and what works and what doesn't in order to get well. It flared up my GERD do now taking Prevacid and going to go to the counselor.. Some people have Graves alone, some have Hashi's alone and some people have both Graves and Hashi's at the same time. I should have listened to him. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. What many people don't realize is that there are quite a few symptoms that can apply to either/both hyper and hypo. Unusual weakness or fatigue, fever, headache, skin rash, muscle or joint pain, loss of appetite, pain, tingling, or numbness in the hands or feet. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. Its been almost a month now on the 2.5 so Im going to get the blood work rechecked within a week or so. Said it was controversial. I stopped Zinc, L-Lysine & alpha lipoic which made me feel amazing! There are experiences, however, that may cause you to question the benefits of your medications and not stick with your treatment plan. Tenner AG, Halvorson KM. Good luck!!! Methods: We retrospectively studied patients with Graves' disease who were initially on MMI, in whom this drug was stopped because they had undetectable thyroid-stimulating antibodies (TSAbs) or were euthyroid after at least 24 months on MMI treatment. Available for Android and iOS devices. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Side effects are also most likely to occur within the first three months of treatment, so keep that in mind if you are beginning a new regimen. I am at 15 MG per weekI take 5 mg on M/W/F and my body is getting used to it but I have passed the two year mark and no signs of it abating. I feel fine. My TSH plunged this year after Tom's death and all my health scares (the eye bleeds - occular migraines - vertigo - stroke scare which turned out to be migraine aura - ugh) This must have tipped me into real hyper maybe graves. She is the author of "The Thyroid Diet Revolution.". Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. But don't tapper too much and too fast. There are a number of strategies you can use toremember to take your thyroid medication. Her overall presentation does not seem to add up in being secondary to urosepsis. Her vital signs are blood pressure of 184/106 mmHg, heart rate of 130 beats per minute, respiratory rate of 22 breaths per minute, and temperature of 102.7F. HyperT77 My Endocrinologist has started weaning me off of Methimazole. not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in Do not use methimazole in larger or smaller amounts or for longer than recommended. So this is a surprise to me that I migh have Graves or toxic nodules as I feel I'm bouncing back with no symptoms of hyper. Please get back to me.. I read somewhere that ALA can work on TSH. Shaky? I agree, doctor should have told you this. no one will listen. with 87 to 100 percent becoming euthyroid within a few weeks to a few months . 2 days on, one day off and this past week my endocrinologist gave me the choice of either going right off Tapazole or going off it slowly. So hopefully youre getting bloodwork again soon to make sure things are ok? When I stopped in 2015, I went hyper againin approx 8 months, so after a lotof readingand research, I've decided to taper my dose rather than stopping. As soon as they see that youre going hyper again, they should put you back on your regular dose. Drug class: Antithyroid agents. Overdose symptoms may include nausea, vomiting, upset stomach, headache, joint pain, fever, itching, swelling, or pale skin and easy bruising or bleeding. For oral dosage form (tablets): For hyperthyroidism: AdultsAt first, 15 to 60 milligrams (mg) per day, given in 3 divided doses about every 8 hours. Treatment and prognosis of Graves disease in children and adolescents. Do not take extra medicine to make up the missed dose. I never was given clarity about what "the damage" entailed though:(. But it can also cause weight loss and a reduced need for sleep, which some people actually welcome. However, since starting to wean off, my numbers have gotten closer to the Hyper T side again. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. upper right abdominal pain. All of this has been a real struggle for me since I have a huge phobia of taking meds. Additional benefit of PTU in thyroid storm: Inhibition of the peripheral conversion of T4 to T3 (3rdB), PTU and MMI can both be administered through the rectal route as a suppository and retention enema, Shown to have good response in several trials, Intravenous (IV) thionamides are currently not commercially available in the United States, IV formulation of MMI is available in Europe, Success reported in case reports and case series of treating thyroid storm with IV MMI compounded formulations, PTU: black box warning for severe and/or life-threatening hepatotoxicity issued by FDA in 2010, Tends to be dose-related with MMI, unlike PTU, Granulocyte colony-stimulating factors (G-CSFs) can be used in the management of thionamide-induced agranulocytosis, Used to prevent the release of pre-formed thyroid hormone from the thyroid gland, Administration of inorganic iodine should be delayed for at least one hour after initiation of thionamide therapy, Iodine load can serve as a substrate for thyroid hormone synthesis and exacerbate thyroid storm, Iodine content of formations (NOTE: Solutions, Dissolve the dose in solution of 3 to 4 ounces of milk, fruit juice, or water to ensure that the full dose is given and to mask the bitter taste. Your number for what was 2.13? Ok. We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. If you are on a beta blocker for your heart rate (propranolol, atenolol, metoprolol, etc), your doctor may discontinue, decrease the dose, or keep the dose the same with plans to wean the medication in the weeks and . Emerg Med ClinNorth Am. It is also used before thyroid surgery or radioactive iodine treatment. Methimazole is usually taken every 8 hours. Went back to 10mg, after 2 consecutive blood tests were good (12 weeks) and then went to 7.5, just did a another 12 week stint, all is good so went to 5 mg this week (very happy). Slowly weaning off or tapering to the right dose is the best method. Endocrine causes of dangerous Fever. ALiEM is your digital connection to the cooperative world of EM. Use of the forums is subject to our Terms of Use We strive to reshape medical education and academia in their evolution beyond the traditional classroom. Found that I could not take vitamin D pills, that they had to be the gel caps. My levels are all in good range so Im confused why she wants to see if I can lower the dose. Take your doses at regular intervals to keep a steady amount of the drug in your body at all times. The screen reading the results was behind me, and I was in a bed. The risk of serious side effects due to thyroid medication is extremely smallfar lower than the risks of remaining untreated. :-). You may need a different medication or a dose adjustment, but you should never quit your medication without your doctor's approval. Most people who have thyroid disease feel better with the appropriate medication. I would ask to do labs again. I was on 5 mg daily and now my dr halved it to 2.5 daily. Hodak S, Huang C, Clarke D, Burman K, Jonklaas J, Janicic-Kharic N. Intravenous methimazole in the treatment of refractory hyperthyroidism. It works by making it harder for the body to make thyroid hormone. Egton Medical Information Systems Limited. I am weaning off methimazole i was only taking 10 mg a day down to 7.5 mg for 2 weeks feeling lightheaded and was wondering if anyone knew of any side effects? Hypothyroidism (underactive thyroid). You have a 54-year-old female who presents to the emergency department with a chief complaint of just feeling out of it. She has felt off and on for the past 12 hours and has had an occasional cough with some sputum production along with the shakes and chills. She also feels as if her heart was going at a mile a minute and because of this, she is very much out of breath.